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Re: jq1234 post# 118310

Thursday, 01/05/2012 10:20:10 PM

Thursday, January 05, 2012 10:20:10 PM

Post# of 257441
GSK licenses phase-2 RA drug from private company, ChemoCentryx:

http://finance.yahoo.com/news/GSK-Exercises-Option-License-prnews-3466860868.html?x=0

CCX354 is a potent and selective antagonist of CCR1, a chemokine receptor that drives the recruitment of certain inflammatory cells including populations of monocytes, macrophages and T cells into the joints of patients with RA. By selectively blocking the CCR1 receptor, CCX354 is designed to reduce the infiltration of inflammatory cells into the joints of RA patients, thus inhibiting the inflammation, swelling, pain and associated joint destruction while minimizing the potential for off-target effects.


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