Biotech Values

[the_busy_ant]

but I don't see any p values or hard numbers (things are very vaguely worded) which would make me cautious if I were long.

"Most authors refer to statistically significant as P < 0.05 and statistically highly significant as P < 0.001 (less than one in a thousand chance of being wrong)."
- ref http://www.statsdirect.com/help/basics/pval.htm

The PR is vaguely worded, however.

"demonstrated highly statistically significant results for the primary endpoint in two of the three treatment arms[OK p < 0.001, but which doses?] when compared to the placebo treatment arm"


"Both the 300 and 450 mg treatment arms[Here, they are very specific about which doses were p < 0.001] demonstrated highly statistically significant improvements in rescue-free bowel movement (RFBM) within 4 hours of administration over 28 days of dosing when compared to placebo treatment."


"Statistically significant efficacy was also seen in both the 300 and 450 mg treatment groups for the two key secondary efficacy endpoints including one assessing response (responder/non-responder) to study drug during Weeks 1 to 4 where “responder” is defined as having 3 or more RFBMs per week, with an increase of at least one RFBM per week over baseline, for at least 3 out of the first 4 weeks.". Were there any secondary endpoints where stat sig wasn't met?

I don't know much about Relistor or PGNX, but I'm reasonably adept at reading a PR in a skeptical fashion.