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Re: Orangenation5 post# 133262

Saturday, 12/17/2011 9:55:03 PM

Saturday, December 17, 2011 9:55:03 PM

Post# of 257580

That's a bold statement to make. Just because one guanosine shows tox doesn't mean all the others in current pipelines will - or that adenosine's will succumb to the same fate. It could be a class issue, or maybe not




Maybe you misunderstood my statement. VRUS was the only company clinically testing two nukes in an oral combination.



If it is, is it a purine class issue or a guanosine class issue?




Most (if not all) HCV purine analogs still in development are guanosine so I used the broader term.


There are other companies actively looking into dual-nuke with data in the foreseeable future.



I don't know of any. I'm aware of certain companies that have two nukes in their pipeline. None of which are clinically testing a dual-nuke oral combo.


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