Biotech Values

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MNTA European/U.S. Patent Applications Update for RMF - Plus MNTA Overview of their Patent Estate -

1.Evaluating mixtures of low molecular weight heparins by chain profiles or chain mapping 2011-12-13

Abstract:
Methods for analyzing mixtures of polysaccharides, for example heparin such as unfractionated heparin and enoxaparin are described. In some instances, the mixtures are analyzed using fast performance liquid chromatography (FPLC) and high liquid performance chromatography (HPLC), e.g., strong anion exchange HPLC.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20111213&CC=US&NR=8076149B1&KC=B1

2.GALACTOSE-ALPHA-1, 3-GALACTOSE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS 2011-11-30

Abstract:
The present invention provides methods for evaluating a Chinese Hamster Ovary (CHO) cell population by measuring glycans containing terminal galactose-alpha-1-3-galactose residues produced by said cells, wherein the CHO cells have not been genetically engineered to express an alpha-galactosyl transferase coding sequence.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&adjacent=true&locale=en_EP&FT=D&date=20111130&CC=EP&NR=2389586A1&KC=A1

3.ANALYSIS OF SULFATED POLYSACCHRIDES 2011-11-24

Abstract:
The invention relates to methods and products associated with analyzing and monitoring heterogeneous populations of sulfated polysaccharides. In particular therapeutic heparin products including low molecular weight heparin products and methods of analyzing and monitoring these products are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&adjacent=true&locale=en_EP&FT=D&date=20111124&CC=US&NR=2011288046A1&KC=A1

4.CHARACTERIZATION OF O-LINKED GLYCANS 2011-11-24

Abstract:
The present disclosure provides methods for analyzing structure and/or composition of glycoproteins and glycans of glycoproteins. Such methods can include subjecting a glycoprotein preparation to a condition that removes at least one O-linked glycan from the glycoprotein. Such methods can include subjecting a glycoprotein preparation to a condition that releases an N-glycan from the glycoprotein, e.g., prior to subjecting the glycoprotein to a condition that releases an O-glycan from the glycoprotein.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&adjacent=true&locale=en_EP&FT=D&date=20111124&CC=US&NR=2011287465A1&KC=A1

5.GLYCOSYL TRANSFERASE FROM CHINESE HAMSTER AND RELATED METHODS 2011-11-10

Abstract:
A glycosyl transferase from Chinese hamster and related methods are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=2&adjacent=true&locale=en_EP&FT=D&date=20111110&CC=US&NR=2011275526A1&KC=A1

6.MS METHODS TO EVALUATE GLYCANS 2011-10-28

Abstract not available

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&adjacent=true&locale=en_EP&FT=D&date=20111028&CC=SI&NR=2135091T1&KC=T1

7.Copolymer assay 2011-10-26

Abstract:
The present invention provides methods and compositions for evaluating one or more properties of an amino acid copolymer.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=2&adjacent=true&locale=en_EP&FT=D&date=20111026&CC=EP&NR=2381254A1&KC=A1

8.TISSUE TARGETING 2011-10-20

Abstract:
Methods and compositions related to targeting agents to tumor tissue are described.

http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20111020&DB=EPODOC&locale=en_EP&CC=WO&NR=2011130697A2&KC=A2

9.SELECTION AND USE OF HOST CELLS FOR PRODUCTION OF GLYCOPROTEINS 2011-10-13

Abstract:
A method of making a glycoprotein having a selected glycostructure.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&adjacent=true&locale=en_EP&FT=D&date=20111013&CC=WO&NR=2011127325A1&KC=A1

10.HIGH MANNOSE GLYCANS 2011-10-13

Abstract:
Methods and compositions related to high mannose glycans are described.

http://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=1&adjacent=true&locale=en_EP&FT=D&date=20111013&CC=WO&NR=2011127322A1&KC=A1

PATENTS

Over 100 patents give Momenta a strong proprietary position.
Momenta possesses a strong intellectual property position around our characterization platform. We license or own a total of over 100 patents and patent applications. Our patent portfolio includes claims covering:

•methods and technologies for characterizing sugars;
•the use of certain enzymes and reagents that specifically recognize polysaccharides in the characterization of sugars;
•methods and technologies for chemical and metabolic synthesis of sugars;
•the composition of matter of certain novel low-molecular-weight herapins (LMWHs), including M118, and heparinase variants;
•methods to produce and identify sugars associated with glycoproteins;
•methods to analyze and monitor glycoprotein profiles for purposes associated with the diagnosis, staging, prognosis and monitoring of cancer; and
•methods for the in vivo non-invasive delivery of sugars.
We also rely on trade secrets, know-how, continuing technological innovation and in-licensing opportunities to develop and maintain our proprietary position

http://www.momentapharma.com/technology/patents.html