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Re: iwfal post# 131901

Monday, 11/28/2011 9:26:57 AM

Monday, November 28, 2011 9:26:57 AM

Post# of 257300
And these results should put a damper on that thinking since 0.69 is a HR that would have been passed had the trial been running as long as contended (factor of >=2x was the contention) due to treatment being a miraculous cure.

It certainly means that RFA has improved a lot in the last 5 or so years... if the HR was higher than .69 at the interim look, and the modeling is roughly correct (assuming constant hazard rate), I think it forces median control PFS comfortably over 18 months.

That would be consistent with the Chinese meta-analysis we talked about awhile back.

“The trick is in what one emphasizes. We either make ourselves miserable, or we make ourselves happy. The amount of work is the same.” Carlos Castaneda

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