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Re: pcrutch post# 131129

Tuesday, 11/15/2011 3:52:26 PM

Tuesday, November 15, 2011 3:52:26 PM

Post# of 257271
Re: SVR24 vs SVR12

The positive predictive value (PPV) between SVR12 and SVR24 measurements was 98% and the negative predictive value (NPV) was 99%.

Moreover, I would submit that these numbers are trending even higher as HCV regimens become better and better.

SVR24 was a reasonable primary endpoint in the bad old days of treatment for 48 weeks with only interferon + ribavirin, but it’s overkill today, IMO.

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