Management noted that in a recent Roche trial, DTIC showed overall survival in BRAF melanoma patients of about 8 months. The Phase 2 combo selumetinib trial in BRAF melanoma patients has still not reached the pre-specified number of events and top-line results are now not expected until 1H2012. (The trial completed enrollment over 18 months ago.)
oh well, i'll try not to get too excited about that. a couple more things that i liked and are new to me:
slide 11, potential size of KRAS mutant NSCLC market: 1 billion (thought it was much smaller) slide 10, selumetinib royalty: potential double-digits (since it's such an old collaboration and they had never mentioned it, i had assumed it was single-digits)
big believer in ARRY and mostly in their MEK inhibitors used in combination. mcbio: thanks for all the useful information.