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Re: mcbio post# 128588

Monday, 10/17/2011 9:06:48 AM

Monday, October 17, 2011 9:06:48 AM

Post# of 257406

What else does Roche have in the HCV space to pair with a non-nuke?





Roche has RG7432 which is a nucleotide inhibitor in phase 1. If this nuke falls short in efficacy as a mono-therapy maybe setrobuvir would be a safe DAA addition? Safety and its mid-stage status are the only two desirable aspects I see to the drug. I doubt danoprevir and mericitabine will be used with setrobuvir and I would consider this part of the rebirth of Roche's HVC program.

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