iwfal, re my bad attitude:
First, that wasn't the only RFA case I'd looked at. It had just been a long while, and I was in a hurry. The "bear case" you found IS the big one that CLSN longs worry about.
Regarding your "quiz", I'd take the safe drug then if it failed, I'd take the one with side effects. It would make my overall chance of surviving 70% + 30% x 80%, or 94%.
My contention about the board was exaggerated. But there is a lot of that here -- meaning, finding ways to dismiss certain stock ideas. TSPT was a good example. If you read the press release, and didn't apply heavy skepticism re mgmt, and looked at the B/S, it was a great risk/reward. Co had a TON of cash, and therefore tons of staying power, and a surmountable FDA issue.
That one was my fault. I should have followed my instincts.
“The trick is in what one emphasizes. We either make ourselves miserable, or we make ourselves happy. The amount of work is the same.” Carlos Castaneda