Biotech Values

[jq1234]

It entered phase 1 over three years ago. If that tells us anything.

Have you followed other ADC phase I dose escalation trials before? They do take much longer to find maximum tolerated dose. ADC in a sense is combo drug trial, it needs to start at relatively low dose, escalating dose very slowly. Roche/IMGN's T-DM took a long time even though part of the drug trastuzumab was an approved drug for the same validated target. Even SGEN's SGN30 for liquid tumor took a long time in phase I.

Antibody drugs in general take much longer to develope than small molecule drugs, but the success rates are much higher as well. Thus, time taken to develope doesn't tell you about the chance to succeed.