Biotech Values

[projectchris]

I really don't see reduced osteoclastic activity in late-stage patients without known bone mets as concerning at all. It's cerainly plausible these patients have occult bone mets which haven't yet shown up on a scint scan. Be nice to know if their pre-treatment CTx levels were elevated.

journals.lww.com/corr/Abstract/2003/10001/Diagnosis_of_Occult_Bone_Metastases__Positron.16.aspx

Peter

I personally don't either. I also find the rise in hemoglobin with non metastatic bone disease as interesting for anemic patients. I wonder if metastatic crowding is occurring on micro/occult level in bone marrow much like you describe could be happening with regards to elevated CTx levels.