According to NVS’ 2Q11 CC, 55% of US Gilenya patients were previously taking no drug for MS, and 45% of Gilenya patients switched from another drug. Of the 45% who switched, ~38% (i.e. 17% of US Gilenya patients) switched from Copaxone, as can be seen from the chart below. Thus, each US patient start on Gilenya is subtracting 0.17 from the number of patients taking Copaxone. This number increased from NVS’ estimate of 0.125-0.15 patients six months ago (#msg-59293907).
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