No need to apologize. Amgen has several unexpired G-CSF PEGylation patents in the US 5,824,778, US 5,824,784 (the one you've found), US 6,166,183. From a quick look i suspect they only cover PEGylation when PEG molecule is attached to any amino acid via a carboxyl group at the N-terminus of the protein. Ratiopharm uses a different PEGylation method. See also #msg-65405618
Register for free to join our community of investors and share your ideas. You will also get access to streaming quotes, interactive charts, trades, portfolio, live options flow and more tools.