These drugs are competitors for the non-TNF-a segment of the RA market, usually in the third-line setting (following methotrexate in the first line and one of the TNF-a drugs in the second line). Roche’s Actemra is a distant third to Orencia and Rituxan in this market segment.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”