Just to echo Dew's comments a bit. In addition to side effects if you look at some of the risks (e.g. higher risk of Lymphoma) I would be a bit concerned taking (or having family take) Humira and I believe most if not all the other RA drugs too. So, I suspect there are a fair number of RA patients too who are reluctant to start especially if outbreaks/symptoms are not frequent and/or milder.