I've never believed it very likely that niacin's efficacy, assuming there is any, is through HDL.
Are you saying that you do not accept reverse-lipid-transport as a valid MoA and property of HDL's? Or do you have another reason?
At this point I have over 10 years on Niaspan (and statins) which has given me a sense of security that may be false.
Should I get a check up or just have my body donated to science?
ij
It is astonishing what foolish things one can temporarily believe if one thinks too long alone ... where it is often impossible to bring one's ideas to a conclusive test either formal or experimental. J.M. Keynes
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