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Re: BTH post# 120265

Wednesday, 05/18/2011 11:13:51 PM

Wednesday, May 18, 2011 11:13:51 PM

Post# of 257579

Do you think that there is a mutated gene for every cancer out there and its just a matter of finding the switch to turn it off like they have been able to do with ALK and BCR.ABL, and Hh?



No - examples like ALK and BCR/ABL are the exceptions rather than the rule. In most cancers there is a lot more going on than a single gene stuck in the "on" position.

But you might yet see more magic with the right combination therapy in these more complex cancers.

Peter

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