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Re: krenjp post# 10751

Thursday, 05/05/2005 1:11:59 AM

Thursday, May 05, 2005 1:11:59 AM

Post# of 257268
Thanks for initiating an interesting thread.

The increased productivity of mAb cell lines in recent years is a well-known phenomenon and is perhaps the major reason for the current glut in mAb production facilities. (The withdrawal of Tysabri and the buildout of DNA’s Vacaville plant are also significant factors.)

However, as PGS stated, the kinds of proteins that GTCB expects to produce commercially (e.g. ATryn, rhAAT, AFP) have distinct production characteristics from mAbs and ought to be considered an entirely separate sub-market within the overall realm of biopharmaceutical manufacturing. Regards, Dew

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