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Re: DewDiligence post# 118428

Monday, 04/18/2011 10:19:44 PM

Monday, April 18, 2011 10:19:44 PM

Post# of 253145

Although comparison is muddied by differences in the patient pools, today’s AMR101 results do seem to exacerbate the already difficult sales pitch for TriCor/TriLipix. That’s why I mused in an earlier post today that ABT might be the most logical suitor for AMRN.



It isn't settled yet in my opinion. Except safety profile, Tricor's number for reduction of triglyceride and LDL-C looked much more impressive. However, outcome trials didn't come out favorable. The main risk with AMRN reaching its potential valuation is the outcome trial. FDA requires the trial to be substantially underway before approval in 200-500mg/dl TG population. So outcome trial result will be out just a few short years after AMR101 coming to market. I don't think ABT would want to have two drugs for same purpose, but two negative outcome trials in hand.
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