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Re: DewDiligence post# 117978

Saturday, 04/09/2011 10:30:37 PM

Saturday, April 09, 2011 10:30:37 PM

Post# of 257426

When PhRMA released its first accounting of medicines in development for cancer in 1988, only 65 were recorded. The numbers over the next decade grew gradually. As recently as 2005, there were fewer than 400 medicines in development for cancer.



Wow!

While I knew number of cancer drugs in clinical trials increased dramatically the last 5 years based on personal obeservation, it's still good to have actual number backing it up.

As I mentioned in message (#115523), this was the major contributing factor to the dramatic decline of overall drug development success rate.

I believe drug development area goes through cycles. Everyone is getting into oncology in recent years. However, unless success rate goes up dramatically - via personalized (biomarker) route - the current trend is not sustainable.

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