Assuming the apparent effect is real(!!) (at this point a small dataset but nonetheless a reasonably sized effect) my speculation is that the effect is a result the following…
In phase-3 trials and in actual clinical practice (should these regimens get to that point), I highly doubt that any all-oral HCV cocktails will be dosed in a sequential fashion.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”