…making it difficult for the new orals to be added to hospital protocol as a first-line prophylaxsis choice.
Agreed. The one exception may be where the alternative to one of the new oral anticoagulants is warfarin; however, warfarin isn’t widely used in the hospital setting, so this isn’t much of a business opportunity.
In the outpatient setting, on the other hand, the new oral anticoagulants will almost certainly become big-selling drugs, IMO.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”