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Re: io_io post# 10438

Thursday, 04/28/2005 9:31:08 PM

Thursday, April 28, 2005 9:31:08 PM

Post# of 257268
>>But I see that you mention a theory that they can reduce or eliminate patient antibodies in biologics (relative to conventional methods I presume) - on what basis does this theory exist ?<<

io: That would be nice, but I didn’t say that and I don’t think Urche did (although he can speak for himself).

We do know that none of the 200+ patents treated with ATryn has developed anti-ATryn antibodies. However, this merely means that anti-ATryn antibody formation should become a non-issue – it does not mean that ATryn is superior to plasma-based antithrombin on this score.

The reason that ATryn is safer than plasma-based antithrombin is that ATryn carries no risk of transmitting pathogens that can be carried in human blood. Regards, Dew

p.s. Also see #msg-4988136.

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