NanoViricides Inc (NNVC)

[BonelessCat]

>>"and HIV drugs are still one pill once a day with no side effects."

This statement alone is so lacking in credibility, factuality, and authority that it renders every other statement... Well, you get the picture.

HIV replication material shifts, recombines and mutates so that any treatment is only effective for so long. Every treatment. Here are three sources on the topic:

Mechanistic Features of Recombination in HIV
Román Galetto and Matteo Negroni |Full Article in PDF|
Unité de Régulation Enzymatique des Activités Cellulaires. CNRS-URA 2185. Institut Pasteur. Paris, France
aidsreviews.com/resumen.asp?id=841&indice=200572&u=unp

Recombination favors the evolution of drug resistance in
HIV-1 during antiretroviral therapy
http://darwin.uvigo.es/download/papers/56.recModelHIV07.pdf

Accurately Measuring Recombination between Closely Related HIV-1 Genomes
http://www.ploscompbiol.org/article/info:doi%2F10.1371%2Fjournal.pcbi.1000766

Second, to use your own words, every drug has side effects, and all current HIV drugs have side effects and toxicity that must be closely monitored even at therapeutic levels. Yes, Atripla is well-tolerated in the clinical sense when compared to other HIV drugs, but that is only when compared to the alternative of not taking any drugs. Some more sources:

Atripla: http://www.hivandhepatitis.com/hiv_and_aids/atripla1.html#adv

"No, drug resistance is not inevitable. The best evidence that you could go for many years on this same regimen without resistance, provided you maintain excellent adherence, is to be found in long term clinical trials of this regimen. After 5 years in one extended study of this regimen, more than two thirds of people who started on this regimen were still well controlled. If you are able to maintain excellent adherence, you could well have full suppression after 5 or more years on this regimen." --Renslow Sherer, MD, University of Chicago
http://www.thebody.com/Forums/AIDS/Resistance/Q189790.html

The good doctor is putting a happy face on the inverse; 1/3rd of all patients in the 5 year study developed Atripla resistant HIV. There is already a need for a drug to replace Atripla for those 1/3rd of all patients who develop resistance.