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Re: genisi post# 116681

Sunday, 03/20/2011 7:33:00 AM

Sunday, March 20, 2011 7:33:00 AM

Post# of 252475

In the EU, Shire's Firazyr label was recently amended to include self administration as well, so it's the first and only SubQ self administered agent for acute HAE, an advantage that is hard to compete with. If approved with a similar label by the FDA, I expect it to gain a big share in the acute market. This of course will hurt Dyax's Kalbitor and CSL Behring's Berinert but not VPHM’s Cinryze.

Sub-q administration certainly beats having to leave an IV port in the arm, which increases the risk of infection.

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