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Re: biomaven0 post# 115845

Thursday, 03/03/2011 7:56:29 PM

Thursday, March 03, 2011 7:56:29 PM

Post# of 257257
Wikipedia HbA1c quiz—I have a nitpicky objection to the article that is probably not the “serious error” you have in mind. In this statment:

The HbA1c level is proportional to average blood glucose concentration over the previous four weeks to three months…

…I object to the word proportional because there’s a non-zero constant term in the linear relationship between HbA1c and the midpoint of the eAG range, as can be seen in the table that north40000 posted in #msg-60560038. For instance, HbA1c=6% corresponds to an eAG point estimate of 126 mg/dL, while HbA1c=12% corresponds to an eAG point estimate of 298; thus, the 12% number is about 2.4-fold higher than the 6% number (rather than being only twice as much).

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