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Post# of 257264
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genisi

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genisi

Re: mcbio post# 115538

Saturday, 02/26/2011 11:11:14 AM

Saturday, February 26, 2011 11:11:14 AM

Post# of 257264

One patient developed non-neutralizing IgG antibodies to taliglucerase at the end of the study

I believe data were from 25 patients, so the rate of antibodies to uplyso is still lower than that of Cerezyme. See also #msg-56216621. Last point, the non-neutralizing antibodies to Cerezyme have no effect on its safety or efficacy.
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