there are several drugs in development that I am intimately familiar with where th 12 yr exclusivity will be longer than the patent life. Iu think this is becoming more and more common as more people have expertis in biologic and biologics patenting. Many of those older products where able to get patents at or near the time of launch due to the complex and proprietary manufacturing process. there are many novel biologics now in development whose patent life has already started, well before launch