We know from Biomaven's post on stroke...these numbers are simply not big enough to offer significance when the incidence is this low.
Actually, the JELIS reduction in stroke risk was statisg in the secondary-prevention subgroup (HR= 0.80; 95% CI [0.64, 0.997] as per biomaven’s post); however, the method incorporated Cox regression using parameters that may not have been prespecified.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”