Biotech Values

[biomaven0]

>>rida

Combo with mk2206 makes a lot of sense - when you inhibit mTor, Akt gets upregulated and much of the impact of inhibiting mTor is lost. So combo with an Akt inhibitor could be very promising.

I don't understand the combo with Notch though, although this isn't something I've ever looked at. I think Notch and Mtor are basically on the same pathway.

Bottom line though is that this shows MRK is taking this drug very seriously and are doing a very thorough job. Good thing Aria isn't still on the hook for co-development costs.

Peter