Biotech Values

[tinkershaw]

FWIW for the next 42 patients the bone response rate dropped from 95% to 81%. Still appears good - but given the lack of published historical data... .

Isn't this because this data is utterly unprecedented, and therefore there is no published data. From my understanding bone lesion resolutions are a sort of near "miracle" result, a very outlier that you see every once in a while, and here you have 85% of 63 patients with partial or complete resolution (not broken out), and another 8 with stable disease, no progress, meaning that 62/63 patients either had no progression, and the vast majority of patients had at least a partial reversal in bone scans.

It is unprecedented, and just not something anyone else has seen in any numbers. Here you have 85%.

Please correct me if I'm wrong on this, but I think it is an error to critique the results from lack of published historical data, because there has never been any substance that has ever had results anything near these results.

Tinker