Don't know the patent expiries but have to believe an RA FOB is inevitable. Then Rituxan?
The TNF-alpha class includes three biologics among the world’s seven biggest-selling drugs—Remicade (#3), Enbrel (#5), and Humira (#7)—so it’s reasonable to surmise that MNTA has its sights trained on this class. Enbrel is already off-patent in the US, and Remicade will be off-patent soon—long before anyone could bring an FoB to market. Humira goes off-patent in the US in 2016.
Rituxan strikes me as an unattractive FoB program for MNTA because there are already several announced biosimilars and biobetters. Regards, Dew
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”