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Re: alertmeipp post# 35641

Wednesday, 02/02/2011 9:24:44 AM

Wednesday, February 02, 2011 9:24:44 AM

Post# of 57673
Quick take, cautious optimism......

the 2 major burdens of SA are

1)day time vigilance --> NEUTRAL effect(but we will need sequential day therapy assessment. This has to tip into a favorable zone for meaningful benefit justifying chronic drug therapy)

2) cardiovascular(cv) risk --> improved surrogate marker as measured by oxygen desaturation suggests a signal of benefit for cv risk reduction.

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