Biotech Values

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MNTA European/U.S. Patent Applications Update for RMF - Plus MNTA Overview of their Patent Estate -

1. ANALYSIS OF AMINO ACID COPOLYMER COMPOSITIONS 2011-01-26

Abstract:
Methods for analyzing, selecting, characterizing or classifying compositions of a co-polymer, e.g., glatiramer acetate are described. The methods entail analysis of pyro-glutamate in the composition, and, in some methods, comparing the amount of pyro-glutamate present in a composition to a reference standard.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20110126&CC=EP&NR=2277050A1&KC=A1

2. POLYSACCHARIDE COMPOSITIONS AND METHODS OF USE FOR THE TREATMENT AND PREVENTION OF DISORDERS ASSOCIATED WITH PROGENITOR CELL MOBILIZATION 2010-12-23

Abstract:
Polysaccharide preparations lacking substantial anticoagulant activity are provided herein. Methods of making and using such preparations are provided

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20101223&CC=US&NR=2010324276A1&KC=A1

3. Saccharide structures and methods of making and using such structures

Abstract:
Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20091223&CC=AU&NR=2009260434A1&KC=A1

4. METHODS OF MODULATING FUCOSYLATION OF GLYCOPROTEINS 2010-12-09

Abstract:
The present invention provides methods and materials useful for monitoring and regulating the glycosylation of glycoproteins that are recombinantly produced from cells. In particular, methods are provided for monitoring and regulating levels of cellular indicators which affect the level of fucosylation produced by cells.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20101209&CC=WO&NR=2010141855A1&KC=A1

5. PRODUCTION OF GLYCOPROTEINS 2010-12-02

Abstract:
The present invention provides methods and materials by which glycosylation of glycoproteins can be regulated. Methods include the monitoring and regulation of parameters such that a glycoprotein having a desired product quality is obtained.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20101202&CC=WO&NR=2010138502A2&KC=A2

6. METHODS OF ASSESSING ACTIVITY OF A POLYSACCHARIDE COMPOSITIONS 2010-10-21

Abstract:
Methods of assessing polysaccharide preparations lacking substantial anticoagulant activity are provided herein

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20101021&CC=WO&NR=2010121196A1&KC=A1

7. CONTROL OF COPOLYMER COMPOSITIONS 2010-10-07

Abstract:
Methods of making copolymers are described.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20101007&CC=US&NR=2010256039A1&KC=A1

8. METHODS RELATED TO CELL SURFACE GLYCOSYLATION 2010-8-5

Abstract:
The present disclosure provides methods for assessing the glycosylation of a target glycoprotein produced by a cell through analysis of cell-surface glycans on the cell. The present disclosure therefore teaches that glycosylation of cell surface proteins can serve as a proxy for glycosylation of other proteins.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20100805&CC=US&NR=2010196940A1&KC=A1

9. GALACTOSE-ALPHA-1, 3-GALACTOSE-CONTAINING N-GLYCANS IN GLYCOPROTEIN PRODUCTS DERIVED FROM CHO CELLS 2010-7-29

Abstract:
The present invention provides methods for evaluating a Chinese Hamster Ovary (CHO) cell population by measuring glycans containing terminal galactose-alpha-1-3-galactose residues produced by said cells, wherein the CHO cells have not been genetically engineered to express an alpha-galactosyl transferase coding sequence.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3&FT=D&date=20100729&CC=WO&NR=2010085251A1&KC=A1

10. COMPARATIVE ANALYSIS OF PROTEIN CONFORMATIONS BY USING 2D NOESY NMR SPECTRA 2010-7-29

Abstract:
The present disclosure provides a method for determining the relative conformations of a protein provided in different protein preparations, comprising steps of: (i) obtaining a first 2D NOESY NMR spectrum of a first protein preparation; (ii) obtaining a second 2D NOESY NMR spectrum of a second protein preparation; and (iii); determining whether a protein has a different conformation in the first and second protein preparations by comparing one or more cross-peaks in the first 2D NOESY NMR spectrum with one or more corresponding cross-peaks in the second 2D NOESY NMR spectrum.

http://v3.espacenet.com/publicationDetails/biblio?DB=EPODOC&adjacent=true&locale=en_V3FT=D&date=20100729&CC=US&NR=2010188084A1&KC=A1

PATENTS

Over 100 patents give Momenta a strong proprietary position
Momenta possesses a strong intellectual property position around our characterization platform. We license or own a total of over 100 patents and patent applications. Our patent portfolio includes claims covering:

•methods and technologies for characterizing sugars;
•the use of certain enzymes and reagents that specifically recognize polysaccharides in the characterization of sugars;
•methods and technologies for chemical and metabolic synthesis of sugars;
•the composition of matter of certain novel low-molecular-weight herapins (LMWHs), including M118, and heparinase variants;
•methods to produce and identify sugars associated with glycoproteins;
•methods to analyze and monitor glycoprotein profiles for purposes associated with the diagnosis, staging, prognosis and monitoring of cancer; and
•methods for the in vivo non-invasive delivery of sugars.
We also rely on trade secrets, know-how, continuing technological innovation and in-licensing opportunities to develop and maintain our proprietary position

http://www.momentapharma.com/technology/patents.html