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jq1234

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jq1234

Re: mcbio post# 111732

Thursday, 01/13/2011 6:55:30 PM

Thursday, January 13, 2011 6:55:30 PM

Post# of 257654

what specific concerns do you have?



Cardiovascular risk is tough to rule out. The size and length of RIGL trials conducted so far can't rule out cardio risk with increased blood pressure. If R788 works in anti-TNF failure patients, it would change risk/benefit profile for me. If it doesn't, the burden is on them to rule out the cardio risk. Real safety trend won't show up until in larger trial.
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