How many reps will it take to sell Carfilzomib? I can't imagine much more than 100. This isn't the type of drug that costs hundreds of millions for a sales force, far from it. Synergy is great and with Carfilzomib they'll have a drug they (or someone else) can leverage with another product but you don't need more than one drug to be profitable, you just need the right drug. I guess we'll see if carfilzomib is the right drug.