Biotech Values

[DewDiligence]

Thanks for noticing the error—ABT-333 is indeed a non-nuke. I will correct the next revision of the “Most Likely to Succeed” compilation.

…any specific reason why you think so many companies have been focused on non-nukes compared to nukes?

The simple answer is that it’s easier to design a safe and effective non-nuke than a safe and effective nuke. The former merely has to bind to the HCV polymerase, while the latter has to “trick” the polymerase into thinking it’s a bona fide HCV nuke rather than an impostor.