VRUS is not the first company to test an HCV drug with ribavirin without interferon. Idera has been doing it since 2009 (http://clinicaltrials.gov/ct2/show/NCT00990938 ), and Coley Pharmaceuticals (acquired by PFE) did it several years ago.
I stand corrected in my wording. Idera is trying to replace interferon with another immune boosting agent. I'm not familiar with Coley's program but I assume it was similar in nature.
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