Zometa fails to extend DFS in adjuvant breast-cancer trial that tested (chemo)+(aromatase inhibitor) ± Zometa: http://www.reuters.com/article/idUS185738+09-Dec-2010+HUG20101209?feedType=RSS&feedName=huginPressRelease&rpc=43 The failure is not a big deal financially for NVS because Zometa goes off-patent in major countries in about two years.