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Re: exwannabe post# 109941

Friday, 12/03/2010 10:25:32 PM

Friday, December 03, 2010 10:25:32 PM

Post# of 257484

But I suspect the issue is still open. If a drug misses of a PR/CR type primary but CLEALRY hits on OS, it could get approved.



That's when the trial is powered to show OS, and pre-planned for alpha spending for secondary endpoints. Without that, once primary endpoint fails, then statistical significant secondary endpoint is nomimal.

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