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Re: DewDiligence post# 109897

Friday, 12/03/2010 2:10:13 PM

Friday, December 03, 2010 2:10:13 PM

Post# of 257473

All told, EXEL strikes me as a company that’s desperately and prematurely trying to sell XL184 to the investment community as a cancer drug with Avastin-like upside. That could conceivably happen, but the odds are very much against it.



It depends on where you came from. I didn't get the impression they were trying to sell XL184 as a cancer drug with Avastin-like upside. XL184 was left to be dead after BMY walked, and now the RDT data showed great promise. I had low to moderate expectation on XL184 before RDT result. If I had worked on this study, I would be excited as well. Compare XL184 data in CRPC with Provenge and Abiraterone at the same stage, I like XL184's chance. The former showed almost no change to measurable disease, the later showed significantly reduction of PSA.

By the way, I don't even hold EXEL shares right now.

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