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Re: dewophile post# 109681

Wednesday, 12/01/2010 2:29:09 PM

Wednesday, December 01, 2010 2:29:09 PM

Post# of 257580
Do you have any comments on the phase-2b patient pool (stable angina vs unstable angina vs NSTEMI vs STEMI)?

With adequate funding, the best approach would seem to be one phase-2b trial each for unstable angina/NSTEMI and STEMI, especially if the comparator is Angiomax. Such stratification could be important from a mathematical standpoint by enabling the trials to have less statistical noise, and it could be important from a business standpoint because Angiomax usage varies considerably among the sub-indications of ACS.

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