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Re: mcbio post# 106673

Wednesday, 10/20/2010 12:53:31 AM

Wednesday, October 20, 2010 12:53:31 AM

Post# of 257269

I think there is at least some chance that DAAs will eliminate the need for SoC



So do I - in fact I do think it is good odds that at least some HCV treatment paradigms will no longer use IFN/Rib. The question is what percentage no longer use IFN/Rib and when. If we are talking complete elimination (say less than 5% of HCV treatments using IFN/rib) then I would put that at very low odds. Say 5% odds. But the chance of it being unneeded for, say, >50% of treatments then I would give it higher odds. 30%???

And obviously, as the trial results come in I'll change my odds. For instance prior to the recently announced BMY results I'd have given higher odds of elimination from >50% of HCV treatments.

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