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Re: DewDiligence post# 106482

Monday, 10/18/2010 4:08:08 PM

Monday, October 18, 2010 4:08:08 PM

Post# of 257253
Error in the Bloomberg article:

Patients with chronic migraines who took Botox had 7.8 fewer days per month with any headaches, including migraines, compared with 6.4 fewer headache days on placebo, according to a company-funded study released last year.

In separate research, patients getting Botox injections had 9 fewer days of headaches per month, compared with 6.7 fewer with a placebo.



That's not the reduction per month at all, it's the cumulative reduction at 24 weeks (6 months).

So really this is quite a modest effect size - arguably statistically significant but not clinically significant. A couple of neurologists I've discussed this with were generally underwhelmed although they do believe it has some effect.

That said, the market is big and I expect them to now get insurance coverage - previously patients had to self-pay to try this treatment.

Peter

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