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Re: DewDiligence post# 105172

Monday, 10/11/2010 4:55:05 PM

Monday, October 11, 2010 4:55:05 PM

Post# of 257660
PFE’s PF-00299804 pan-HER inhibitor (a/k/a PF-299) shows promising phase-2 interim results in first-line NSCLC, although there are not yet any survival data of consequence:

http://www.reuters.com/article/idCNLDE6961V220101011

PFE is also testing PF-00299804 in a phase-3 trial vs placebo in NSCLC patients who failed prior therapy with Tarceva or Iressa; results are expected in Nov 2012 (http://clinicaltrials.gov/ct2/show/NCT01000025 ).

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