Why do you think a PI has to be part of the combo?
I didn’t say it did; rather, I said Roche evidently thinks a PI is needed and the rest of the industry (except VRUS) appears to agree.
What is wrong with a two-nuke/non-nuke combo or a two-nuke/NS5A inhibitor?
A 3-drug cocktail consisting of a nuke/nuke/NS5A or nuke/nuke/non-nuke might work; what I think is unlikely to work is VRUS’ idea of a 2-drug cocktail consisting of only nukes.
“The efficient-market hypothesis may be the foremost piece of B.S. ever promulgated in any area of human knowledge!”