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Re: rkrw post# 105330

Wednesday, 09/29/2010 11:09:24 AM

Wednesday, September 29, 2010 11:09:24 AM

Post# of 257257

What do you make of the abstract I linked to?



Its a retrospective study which are interesting for further study but thats about it. I don't know the journal per se as to the quality of the manuscripts. This to me seems like case where the literature doesn't seem to mimic the general clinical experience. I will ask several cardiac anesthetistsfor there opinion if you like.

The amount of protamine used in CV surgery is very small compared to its overall use. Dialysis , cardiac and peripheral angiography, non-cardiac vascular surgery. I doubt with bundled dialysis payments there will be much incentive to spend $$ on heparin reversal.

The half life of heparin is about 45 minutes so generally you wait an hour and the problem takes care of it self without the use of protamine.

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