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Re: ghmm post# 104233

Tuesday, 09/14/2010 6:08:08 PM

Tuesday, September 14, 2010 6:08:08 PM

Post# of 257262
ITMN—What I found most noteworthy about the MS webcast was Welch’s all but conceding that ritonavir boosting precludes ITMN-191’s ever being combined with a non-nuke or an NS5A inhibitor. Unlike nukes, these classes of HCV drugs generally use the CYP450 elimination pathway.

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