Biotech Values

[DewDiligence]

Who’s Who in All-Oral HCV Programs

[Updated status of IDIX entry.]

 
          Protease     Other      Non-PI    Dosing 
 Company  Inhibitor   Compound    Class    Frequency  Link 
 VRTX     Telaprevir  VX-222     non-nuke    BID      http://clinicaltrials.gov/ct2/show/NCT01080222 
 Roche    ITMN-191    RG7128       nuke     TID/BID   http://clinicaltrials.gov/ct2/show/NCT00801255 
 BMY      BMS-650032  BMS-790052   NS5A      BID      http://clinicaltrials.gov/ct2/show/NCT01012895 
 B-I      BI 201335   BI 207127  non-nuke   TID/BID   http://clinicaltrials.gov/ct2/show/NCT01132313 
 IDIX†    IDX320      IDX184       nuke       qD      † 
 ACHN     ACH-1625    ACH-2928     NS5A       qD      * 
 VRUS       n/a       PSI-7977   nuke/nuke    qD      * 
                     +PSI-938 

*All-oral trial has not started.
†Program on clinical hold pending FDA review of SAE’s in drug-drug-interaction study.