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drbio45

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drbio45

Re: BTH post# 102671

Thursday, 08/26/2010 7:27:41 PM

Thursday, August 26, 2010 7:27:41 PM

Post# of 252398
are you saying that the two trials that genentech ran were not in indications driven by the hedgehog mutation, even though the drug targets the hedgehog pathway.

why would Genentech pursue this? I thought they loved targeted therapies? They orignially tried Herceptin in all breast cancer patients and then found that it only works in breast cancer that overexpressed her2.

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